| Worm Food | Not Achieved | Win a game by eradicating humanity with the Neurax Worm | |
| Not Another Zombie Game | Not Achieved | Win a game with the Necroa Virus without making a single zombie | |
| The Glorious Dead | Not Achieved | Win a game with the Necroa Virus | |
| Insane Bolt | Not Achieved | Sprint to victory and set a world record by winning the game with Bacteria in under 365 days | |
| Bacteria Victory | Achieved | Win a game with Bacteria on Normal Difficulty or higher | 369 days 23 hours ago |
| Virus Victory | Not Achieved | Win a game with Virus on Normal Difficulty or higher | |
| Fungus Victory | Not Achieved | Win a game with Fungus on Normal Difficulty or higher | |
| Parasite Victory | Not Achieved | Win a game with Parasite on Normal Difficulty or higher | |
| Prion Victory | Not Achieved | Win a game with Prion on Normal Difficulty or higher | |
| Nano-Virus Victory | Not Achieved | Win a game with Nano-Virus on Normal Difficulty or higher | |
| Unlock Cheatmodes | Not Achieved | Unlock the cheats by winning a game on Normal for ALL disease types | |
| Banana Skin | Not Achieved | Prevent PfiGlax modifing the Necroa Virus | |
| Big Bang | Not Achieved | Kill the DarkWater research team | |
| Bottle Smasher | Achieved | Smash a Blue cure bubble and slow down the Research Team | 2783 days 14 hours ago |
| Brainzzzz | Achieved | Discover the Waking Dead combo | 2783 days 14 hours ago |
| Breathe Deep | Not Achieved | Infect the Chernobyl research team | |
| Brown Streets | Not Achieved | Discover the Public Defecation combo | |
| Chinese Nuclear Retaliation | Not Achieved | Make the USA nuke China | |
| Contaminated Package | Not Achieved | Let humans spread the disease via blood transfusion | |
| Dead End | Not Achieved | Stop DarkWater from discovering a Necroa Virus weakness | |
| Don't Ask Me | Not Achieved | Make the PfiGlax modification project fail | |
| Due Diligence | Not Achieved | Stop PfiGlax finding a link to the Necroa Virus | |
| Evolve your disease | Achieved | Evolve your disease to become stronger | 2783 days 14 hours ago |
| Flash Mob | Not Achieved | Successfully use the Zombie Horde active ability | |
| Getting Colder | Not Achieved | Trick the Egyptian DNA tests | |
| Hide and Seek | Not Achieved | Prevent link with Chernobyl exclusion zone | |
| I'll Be Back | Not Achieved | Successfully use the Zombie re-animate active ability | |
| Is it a bird? | Not Achieved | Discover the Vampire Bat combo | |
| It's a Trap! | Not Achieved | Wipe out the Giza expedition | |
| Jaws | Not Achieved | Discover the Blood in the Air combo | |
| Long Shot | Not Achieved | Discover the Projectile Vomiting combo | |
| Non Starter | Not Achieved | Stop DarkWater from analysing the Necroa Virus | |
| Oink oink | Not Achieved | Discover the Swineflu Combo | |
| Olympic Spoiler | Achieved | Help the Olympics go viral | 2783 days 14 hours ago |
| Patient Who? | Not Achieved | Stop the CDC finding Patient Zero | |
| Peer Pressure | Not Achieved | Have your plague discovered after riots force a government investigation | |
| Plague in Space | Not Achieved | Infect astronauts before they launch a space mission | |
| Red Rain | Not Achieved | Discover the Profuse Bleeding combo | |
| Revenge of Osiris | Not Achieved | Invalidate the knowledge of the pharaohs | |
| RMS Watch List | Achieved | Get your Plague on the RMS Watch List | 2783 days 14 hours ago |
| Runner | Not Achieved | Discover the Runner combo | |
| Russian Nuclear Retaliation | Not Achieved | Make the USA nuke Russia | |
| Spitter | Not Achieved | Discover the Spitter combo | |
| STALKERs delight | Not Achieved | Cause a nuclear meltdown | |
| Tank | Not Achieved | Discover the Tank combo | |
| Tasty | Not Achieved | Discover the Bath Time combo | |
| Test This! | Not Achieved | Force Chernobyl research to be put on hold | |
| The End Plague | Achieved | Win one game with any disease type and any difficulty | 1865 days 13 hours ago |
| Touchscreen Trash | Not Achieved | Disrupt the iCure and stop it helping cure research | |
| Uh Oh | Not Achieved | Discover the Oops symptom combo | |
| Use your head | Not Achieved | Discover the Cranial Dispersion combo | |
| Walking Contradiction | Not Achieved | Discover the Walking Contradiction combo | |
| Who needs DEET | Not Achieved | Avoid insect bites | |
| Z Com: Enemy Undead | Not Achieved | Destroy a Z Com fortress | |
| Assuming Direct Control | Not Achieved | Win a game by enslaving humanity with the Neurax Worm | |
| Neurax Worm Victory | Not Achieved | Win a game with Neurax Worm on Normal Difficulty or higher | |
| Bio-Weapon Victory | Not Achieved | Win a game with Bio-Weapon on Normal Difficulty or higher | |
| Complete Black Death | Not Achieved | Score 3 biohazards with Black Death scenario | |
| Complete Created Equal | Not Achieved | Score 3 biohazards with Created Equal scenario | |
| Complete Global Warming | Not Achieved | Score 3 biohazards with Global Warming scenario | |
| Complete Golden Age | Not Achieved | Score 3 biohazards with Golden Age scenario | |
| Complete Ice Age | Not Achieved | Score 3 biohazards with Ice Age scenario | |
| Complete Mirror Earth | Not Achieved | Score 3 biohazards with Mirror Earth scenario | |
| Complete Pirate Plague | Not Achieved | Score 3 biohazards in the Pirate Plague scenario | |
| Complete Shut Down Everything | Not Achieved | Score 3 biohazards in the Shut Down Everything scenario | |
| Complete Smallpox | Not Achieved | Score 3 biohazards with Smallpox scenario | |
| Complete Sovereign Default | Not Achieved | Score 3 biohazards with Sovereign Default scenario | |
| Complete Swine Flu | Not Achieved | Score 3 biohazards with Swine Flu scenario | |
| Complete Volcanic Ash | Not Achieved | Score 3 biohazards in the Volcanic Ash scenario | |
| Complete Who Cares | Not Achieved | Score 3 biohazards with Who Cares scenario | |
| Complete Xenophobia | Not Achieved | Score 3 biohazards with Xenophobia scenario | |
| Super Sparrow | Not Achieved | Get 3 biohazards with each disease on Normal or higher in the Pirate Plague Scenario | |
| Lava God | Not Achieved | Get 3 biohazards with each disease on Normal or higher in Volcanic Ash scenario | |
| Mr President | Not Achieved | Get 3 biohazards with each disease on Normal or higher in the Shut Down Everything Scenario | |
| Unknown Origin | Not Achieved | Score 3 biohazards with Unknown Origin scenario | |
| Nipah Virus | Not Achieved | Score 3 biohazards with Nipah Virus scenario | |
| Frozen Virus | Not Achieved | Score 3 biohazards with Frozen Virus scenario | |
| Artificial Organs | Not Achieved | Score 3 biohazards with Artificial Organs scenario | |
| Call PETA | Not Achieved | Make a celebrity cry | |
| Contagion Cancelled | Not Achieved | Prevent a film about your plague being made | |
| Who needs Science | Not Achieved | Show the world how useful homeopathy is | |
| Who needs brains | Not Achieved | Take humanity back to the stone age | |
| I never asked for this | Not Achieved | Feel the negative side of artificial organs | |
| Bacteria Master | Not Achieved | Beat Bacteria on mega-brutal difficulty | |
| Virus Master | Not Achieved | Beat Virus disease type on mega-brutal difficulty | |
| Fungus Master | Not Achieved | Beat Fungus disease type on mega-brutal difficulty | |
| Parasite Master | Not Achieved | Beat Parasite disease type on mega-brutal difficulty | |
| Prion Master | Not Achieved | Beat Prion disease type on mega-brutal difficulty | |
| Nano-Virus Master | Not Achieved | Beat Nano-Virus disease type on mega-brutal difficulty | |
| Bioweapon Master | Not Achieved | Beat Bioweapon disease type on mega-brutal difficulty | |
| Neurax Master | Not Achieved | Beat Neurax Worm disease type on mega-brutal difficulty | |
| Necroa Master | Not Achieved | Beat Necroa Virus disease type on mega-brutal difficulty | |
| Normal Shuffle | Not Achieved | Win 5 times in a row on normal difficulty with the shuffle strain enabled | |
| Mega-Brutal Shuffle | Not Achieved | Win 5 times in a row on mega-brutal difficulty with the shuffle strain enabled | |
| Bingo! | Not Achieved | Win 5 times in a row on normal difficulty with the lucky dip strain enabled | |
| Lottery Winner! | Not Achieved | Win 5 times in a row on mega brutal difficulty with the lucky dip strain enabled | |
| Boomer | Not Achieved | Discover the Boomer combo | |
| Apes will Rise! | Not Achieved | Destroy humanity with the Simian Flu and let the apes take over | |
| Not Just a Pretty Face | Not Achieved | Make every ape in the world intelligent | |
| Film Fanatic | Not Achieved | Recreate the setting of the Dawn of the Planet of the Apes film | |
| Great EscApe | Achieved | Break apes out of the primate shelter | 2780 days 10 hours ago |
| Trojan Horse | Not Achieved | Create a trojan plane and use it to infect a new country with the Neurax Worm | |
| Published Scenario | Not Achieved | Publish a Plague Inc:Evolved Scenario to Steam Workshop | |
| Did I mean to do that? | Not Achieved | Reverse Simian evolution | |
| Family. Future. | Achieved | Create an ape colony to bring intelligent apes together | 2780 days 10 hours ago |
| Go Simian-faeces | Not Achieved | Destroy a Gen-Sys lab | |
| The Traveller | Achieved | Move intelligent apes to a new country | 2780 days 10 hours ago |
| EvacuApe | Achieved | Evade a drone attack | 2780 days 10 hours ago |
| Apes. Together. Strong. | Not Achieved | Gather 500,000 apes in a single country | |
| ExterminApe | Not Achieved | Scare humans into becoming hostile to apes | |
| Shouldn't Keep Pets | Not Achieved | Allow all the apes to die | |
| An Ape is for Life… | Not Achieved | …Not just for Christmas | |
| Simian Master | Not Achieved | Beat the Simian Flu on mega-brutal difficulty | |
| No Idea | Not Achieved | Evolve 'Total Brain Death' in the first year and win | |
| Do it like they do | Not Achieved | Discover the Discovery Channel Combo | |
| Ape's Creed | Not Achieved | Discover the Assassin Combo | |
| Like flies round… | Not Achieved | Discover the Fly Magnet Combo | |
| Rude Awakening | Not Achieved | Discover the Rude Awakening Combo | |
| Red Ape Redemption | Not Achieved | Discover the Red Ape Redemption Combo | |
| Blind Genius | Not Achieved | Discover the Blind Genius Combo | |
| Not Necroa | Not Achieved | Discover the Zombie Panic Combo | |
| Attack of the Drones | Not Achieved | Have a colony destroyed by a drone | |
| On The Naughty List | Not Achieved | Put humanity on Santa's naughty list | |
| Ultimate Christmas | Not Achieved | Discover the Ultimate Christmas Combo | |
| Complete Teleportation | Not Achieved | Score 3 biohazards in the Teleportation scenario | |
| Complete Santa's Little Helper | Not Achieved | Score 3 biohazards in the Santa's Little Helper scenario | |
| GLaDOS Says Hi | Not Achieved | Make a teleport attempt end in tragedy | |
| The Future is Bright | Not Achieved | End the game with apes and humans living together peacefully | |
| Genetic Challenger | Achieved | Play a VS multiplayer game through to the end | 2083 days 11 hours ago |
| Genetic Domination | Achieved | Play and win a VS multiplayer game | 1756 days ago |
| Beta Infection | Not Achieved | Play a multiplayer VS game to completion with someone who already has the Beta Infection achievement | |
| Ndemic Infection | Not Achieved | Play a multiplayer VS game with someone who already has the Ndemic Infection | |
| Tutorial | Not Achieved | Complete the Tutorial | |
| Nuclear Warfare | Not Achieved | Launch a Nuclear Strike in a multiplayer game | |
| Brief Acquaintance | Achieved | Play a Co-op multiplayer game through to the end | 2083 days 11 hours ago |
| One Night Stand | Not Achieved | Win a Quick Match Co-op multiplayer game | |
| Friends With benefits | Achieved | Win a Co-op multiplayer game on Casual Difficulty | 1756 days ago |
| BFF | Not Achieved | Win a Co-op multiplayer game on Brutal Difficulty | |
| Comrade-In-Arms | Not Achieved | Win a Co-op multiplayer game on Normal Difficulty | |
| Disease Master | Not Achieved | Complete all disease types on mega-brutal difficulty | |
| Scenario Master | Not Achieved | Score 3 biohazards in every Official scenario | |
| Fully Evolved | Not Achieved | Unlock all other Achievements | |
| Luck of the Devil | Achieved | Destroy a Templar fort with near death vampire | 2781 days 14 hours ago |
| Heart of Darkness | Achieved | Send your vampire into a Blood Rage | 2781 days 20 hours ago |
| Batmobile | Achieved | Transform vampire into a bat and fly somewhere | 2782 days 16 hours ago |
| Vampire Master | Not Achieved | Beat Shadow Plague on mega-brutal difficulty | |
| Blood Pets | Not Achieved | Create slaves for your vampire | |
| Purity of the Chosen | Achieved | Create a new vampire | 2782 days 16 hours ago |
| Home Sweet Home | Achieved | Set up a vampire lair | 2781 days 20 hours ago |
| Van Helsing's Doom | Achieved | Destroy a Templar fort | 2781 days 14 hours ago |
| Twilight Lied | Achieved | Let Humanity discover your vampire | 2782 days 16 hours ago |
| Rock Bottom | Not Achieved | Consume the cavers exploring the Shadow Pool | |
| Watery Grave | Not Achieved | Drown Templar scientists in the Shadow Pool | |
| Pus Explosion | Not Achieved | Oooze pus everywhere! | |
| Wolf Pack | Not Achieved | Hunt down historian searching for Dracula's tomb | |
| I am your Father | Not Achieved | Resurrect Count Dracula | |
| Making Amends | Not Achieved | Help tourists repair the damage to Stonehenge | |
| Greyscale | Not Achieved | Infect Stonehenge explorers | |
| Power Overwhelming | Not Achieved | Consume the bones at Stonehenge | |
| Sadomasochist | Not Achieved | Beat Shadow Plague with no Shadow Slaves | |
| Count Countula | Not Achieved | Carefully count your vampire's feeds | |
| Mr. Universe | Not Achieved | Discover the Mr. Universe Combo | |
| Dark Night | Achieved | Discover the Dark Night Combo | 2782 days 16 hours ago |
| Silent but Deadly | Not Achieved | Discover the Silent but Deadly Combo | |
| Dentist's Dream | Not Achieved | Discover the Dentist's Dream Combo | |
| Uphill Ice Skating | Not Achieved | Discover the Uphill Ice Skating Combo | |
| Evil is a point of view | Not Achieved | Discover the Evil is a point of view Combo | |
| Blood Trumps All | Not Achieved | Discover the Blood Trumps All Combo | |
| Carpe Jugulum | Not Achieved | Discover the Carpe Jugulum Combo | |
| Welcome to Hellmouth | Not Achieved | Discover the Welcome to Hellmouth Combo | |
| Diamond Skin | Not Achieved | Discover the Diamond Skin Combo | |
| Bat Cave | Not Achieved | Discover the Bat Cave Combo | |
| Essential Vitamins | Not Achieved | Discover the Essential Vitamins Combo | |
| Plague Dogs | Not Achieved | Discover the Plague Dogs Combo | |
| Chiroptophobia | Not Achieved | Drive out cavers before sampling the Shadow Pool | |
| No Brexit | Not Achieved | Stop Britain leaving the EU | |
| Soft Brexit | Not Achieved | Help Britain softly leave the EU | |
| Hard Brexit | Not Achieved | Encourage Britain to have a 'hard' Brexit | |
| Brutal Brexit | Not Achieved | Put Britain on the road to madness when it leaves the EU | |
| Complete Mad Cow Disease | Not Achieved | Score 3 biohazards in the Mad Cow scenario | |
| Sushi Crisis | Not Achieved | Start a Sushi Crisis in Japan | |
| Complete Flight Club | Not Achieved | Score 3 biohazards in the Flight Club scenario | |
| Complete Where is Everyone? | Not Achieved | Score 3 biohazards in the Where is Everyone? scenario | |
| Kind Of A Big Deal | Not Achieved | Discover the Poker board game combo | |
| A Colt Classic | Not Achieved | Discover the Steeplechase board game combo | |
| Infecting Tabletops | Not Achieved | Discover a very familiar board game combo | |
| Sinking Feelings | Not Achieved | Discover the Battleship board game combo | |
| Party Hard | Not Achieved | Discover a compulsory enjoyment board game combo | |
| Taking Risks | Not Achieved | Discover the Risk board game combo | |
| Catan You Believe It? | Not Achieved | Discover the Settlers Of Catan board game combo | |
| Spelling Out Success | Not Achieved | Discover the Scrabble board game combo | |
| Killer Combo | Not Achieved | Discover the Cluedo/Clue board game combo | |
| Anything But Trivial | Not Achieved | Discover the Trivial Pursuit board game combo | |
| Welcome To The Jungle! | Not Achieved | Discover a cursed board game combo | |
| Plague-opoly | Not Achieved | Discover the Monopoly board game combo | |
| Awkward! | Not Achieved | Discover an inappropriate board game combo | |
| Complete Ultimate Board Games | Not Achieved | Score three biohazards in the Ultimate Board Games scenario | |
| Complete Science Denial | Not Achieved | Score three biohazards in the Science Denial scenario | |
| The Cure Is A Lie | Not Achieved | Inspire an anti-cure protest | |
| Making 'heat' waves | Not Achieved | Convince the world there is no environment crisis | |
| Hack Job | Not Achieved | Convince the world that the elections were rigged | |
| Gamergate | Not Achieved | Please don't review bomb us | |
| Generational tension | Not Achieved | Convince the world. Divide the world. | |
| District 9 | Not Achieved | Convince the world that the newcomers don't belong | |
| Independence Day | Not Achieved | Convince the world with an otherworldly threat | |
| Loch Ness Monster | Not Achieved | Convince the world of a legend in the loch | |
| Too cute to lie | Not Achieved | Convince the world it's not feline fine | |
| Filter bubble | Not Achieved | Beat the Fake News Scenario on Normal | |
| Post-truth society | Not Achieved | Beat the Fake News Scenario on Brutal | |
| We love fact checkers | Not Achieved | Get Fact Checked | |
| On the fence | Not Achieved | Tear the world in two with indecision | |
| Bacteria Cured! | Not Achieved | Save the world from Bacteria on any difficulty | |
| Virus Cured! | Not Achieved | Save the world from Virus on any difficulty | |
| Parasite Cured! | Not Achieved | Save the world from Parasite on any difficulty | |
| Nano-Virus Cured! | Not Achieved | Save the world from Nano-Virus on any difficulty | |
| Fungus Cured! | Not Achieved | Save the world from Fungus on any difficulty | |
| Prion Cured! | Not Achieved | Save the world from Prion on any difficulty | |
| Bio-Weapon Cured! | Not Achieved | Save the world from Bio-Weapon on any difficulty with a vaccine | |
| Anti Vaxxer | Not Achieved | Save the world without using a vaccine | |
| Doomsday Save | Not Achieved | Save the world with less than 5% of the world's population left | |
| I will find you | Not Achieved | Investigate a new disease outbreak | |
| Shut down everything | Not Achieved | Do as Madagascar does | |
| In it together | Not Achieved | Initiative combo: In it together | |
| Humans weren't meant to fly | Not Achieved | Initiative combo: Humans weren't meant to fly | |
| We're here to help | Not Achieved | Initiative combo: We're here to help | |
| Report thy neighbour | Not Achieved | Initiative combo: Report thy neighbour | |
| Happy Frogs | Not Achieved | Initiative combo: Happy Frogs | |
| Rules are for losers | Not Achieved | Initiative combo: Rules are for losers | |
| Weapon X | Not Achieved | Initiative combo: Weapon X | |
| Frozen Virus Cured! | Not Achieved | Save the world from Frozen Virus on any difficulty with a vaccine | |
| Support Bubble | Not Achieved | Fund all the special Field Operative upgrades in Frozen Virus | |
| Snow Way | Not Achieved | Try to cover up the DrillZero site | |
| Ice Find | Not Achieved | Study the DrillZero site | |
| Freeze things happen | Not Achieved | Unleash a new outbreak of the Frozen Virus | |